HKBU develops Chinese medicine new formula for treating Alzheimer’s disease
Researchers from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) have developed a Chinese medicine formula named NeuroDefend that offers a potential novel treatment for Alzheimer’s disease (AD). Mouse model experiment results showed that the formula reduces the levels of amyloid-beta (Aβ) and insoluble hyperphosphorylated-tau protein, which are the major hallmarks of AD, in mice brains. It also improves cognitive function and memory in mice.
Professor Li Min, Professor of the Teaching and Research Division and Associate Dean of the School of Chinese Medicine at HKBU (middle); Dr Iyaswamy Ashok, Research Assistant Professor of the School of Chinese Medicine at HKBU (left); Dr K. Senthilkumar, Post-Doctoral Research Fellow of Mr and Mrs Ko Chi Ming Centre for Parkinson s Disease Research at HKBU (right), have developed a Chinese medicine formula named NeuroDefend that offers
2021-02-03 15:05:58 GMT2021-02-03 23:05:58(Beijing Time) Xinhua English
HONG KONG, Feb. 3 (Xinhua) The Hong Kong Baptist University announced on Wednesday that a research team from the School of Chinese Medicine has developed a Chinese medicine formula named NeuroDefend that offers a potential novel treatment for Alzheimer s disease.
Alzheimer s disease is characterized by the senile plaques that are formed by the abnormal accumulation of Aβ, and the neurofibrillary tangles associated with the abnormal accumulation of hyperphosphorylated tau-associated neurofibrillary tangles in the brain.
The university s researchers found that Huang-Lian-Jie-Du-Tang (HLJDT), a traditional Chinese herbal formula comprised of Huang Lian, Huang Qin, Huang Bai and Zhi Zi that is used to treat cerebral ischemia, could significantly reduce Aβ levels in mouse models when Huang Qin was removed.