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Psychedelic compound shows promise in stress relief for socially aggressive mice

A study in Neuropharmacology reveals that a single dose of the psychedelic compound (R)-DOI significantly improves stress-coping behaviors and reduces inflammatory markers in mice subjected to social aggression.

Stress-alternatives-model
Compound
Stress
Amygdala
Anxiety
Rain
Hronic
Ytokine
Depression
Mental-health
Neuropharmacology

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

Massachusetts
United-states
Kateryna-kon
Image-credit
Massachusetts-general-hospital
Heart
Acute-respiratory-distress-syndrome
Flood
Blood-pressure
Cardiomyopathy
Cardiovascular-disease

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

United-kingdom
Science-advances
Image-credit
Coronavirus-disease-covid-19
Antibodies
Flood
D4
Fell
Coronavirus
Ytokine
Ytometry

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

Cancer
Cancer-treatment
Natural-killer-cells
Ioengineering
Flood
One
Bone-marrow
Cart-cell
Fell
Ytokine
Cytotoxicity

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

Milieu-int
Bacillus-calmette-gu
Immune-response
Smoking
Ntigen
Flood
Fell
Coronavirus
Pg
Ytokine
Ytokines

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