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Chromatin architecture reveals vulnerabilities to neurodegenerative movement disorders

L to R) Helen Russell Ph.D., Lavinia Dumitrache Ph.D., Yang Li (seated), Peter McKinnon Ph.D., Aditi Ph.D., Young Don Kwak Ph.D., Susanna Downing A

Peter mckinnonRichard finkelR helen russellSachin katyalAmbika tewariHongjian jinHelen russellKamran khodakhahLavinia dumitracheSusanna downingTimothy shawYang liYoung don kwakJude children research hospitalAlbert einstein college of medicineNational institutes of health

Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage–induced neurodegeneration

Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage–induced neurodegeneration
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Young don kwakIntegrated genomics viewerAllen brain atlasMolecular weight

Accumulated DNA damage linked to neurodegeneration in rare pediatric disorder

From left: Research from Susanna Downing, Young Don Kwak, Ph.D., (standing), Aditi, Ph.D., (seated), Yang Li (standing) and Peter McKinnon, Ph.D

Peter mckinnonRichard finkelHelen russellSusanna downingPatrick schreinerKristin stephensonTimothy shawYoung don kwakYang liJ paul taylorJude centerJude children research hospitalNational institutes of healthPediatric neurological disease researchPediatric neurological diseases researchPediatric translational neuroscience initiative