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Researchers identify molecule that activates cell cycle to enhance cardiac tissue graft production

Researchers identify molecule that activates cell cycle to enhance cardiac tissue graft production
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Manabu kasamotoShunsuke funakoshiYoshinori yoshidaStem cell reportsProfessor shunsuke funakoshiAssociate professor yoshinori yoshida

Altos Labs Announces Sponsored Research Agreement with Kyoto University s CiRA to Foster Cellular Rejuvenation Programming Research

/PRNewswire/ Altos Labs (Altos) today announced that it has signed a sponsored research agreement with the Center for iPS Cell Research and Application.

San francisco bayUnited statesSan diegoUnited kingdomShinya yamanakaKim jamesFinsbury glover heringKnut woltjenYoshinori yoshidaKazutoshi takahashiMorgan warnersAltos senior scientific advisor shinya yamanakaDirector emeritusAltos labsProfessor knut woltjenProfessor yoshinori yoshida

Enhanced muscle regeneration using stem cells

Kyoto University The Hidetoshi Sakurai laboratory reports two new markers that should advance iPS cell therapies for muscle degeneration. Muscular dystrophy describes a group of muscle degenerative congenital diseases. The severity and rates differ between disease and patient, but in all cases the degeneration progresses, sometimes leaving patients in wheelchairs and unable to breathe without artificial respiration. With no present cure, scientists are experimenting with the transplantation of muscle progenitor cells, but the amounts needed can only be made from stem cells such as iPS cells. A new study by CiRA Associate Professor Hidetoshi Sakurai and colleagues report two cell surface receptors, CDH13 and FGFR4, that are expected to advance iPS cell therapies for these diseases.

Mingming zhaoAkitsu hottaNaoshi sugimotoAntonio lucena cacaceTatsuya jonouchiHidetoshi sakuraiTakuma mizusawaMitsuru sasaki hondaMinas nalbandianMasahiko yasudaYoshinori yoshidaDepartment of clinical applicationKyoto universityCentral institute for experimental animalsDepartment of cell growthProfessor hidetoshi sakurai