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In 2020, Gray Optics saw a surge in demand from manufacturers of COVID-19 point-of-care tests.
Founded in 2017, the Portland company develops advanced imaging technologies and optical systems for biomedical, life sciences and industrial applications.
With the pandemic, manufacturers of point-of-care tests, which provide disease detection and diagnosis within minutes, asked founder Daniel Gray and his team to design custom optical systems that are an integral part of the tests.
The challenge? Many rapid tests rely on fluorescence detection using a lens that must be precisely aligned, with regard to specifications such as field-of-view and depth-of-field, to a digital image sensor.
“The presence of COVID can be detected through fluorescence imaging: In simple terms, does the sample glow a specific color or not?” says Gray.
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Yokogawa Fluid Imaging Technologies, Inc. manufactures industry-leading particle analysis instrumentation based on digital imaging technology. Our flagship product, the FlowCam, is the first automated particle analysis instrument to use digital imaging for measuring size and shape of microscopic particles in a fluid medium. With applications in oceanographic research, municipal water, biopharmaceutical formulations, chemicals, oil and gas, biofuels and many other markets, YFT continues to lead the way in imaging particle analysis.
The FlowCam is in use by the U.S. EPA, FDA, Pfizer, Amgen, Heinz, Nestle, Apache, and Scripps Institution of Oceanography, among hundreds of other organizations in over 40 countries and on every continent.
Fiber Analysis and Flow Imaging Microscopy
The analysis of fibrous particles has always presented a challenge. In systems that are volumetrically based like Coulter Counters, laser diffraction, and dynamic light scattering, Equivalent Spherical Diameter (ESD) is the only measurement provided, which is clearly not useful for fibers (example shown in Figure 1).
Due to this drawback, manual microscopy has been the main technique for the characterization of fibers where both width and length are analyzed. This process can be made dramatically quicker through the use of Flow Imaging Microscopy where computer algorithms are used instead of a human observer. Figure 2 presents the overview results of a FlowCam
The FlowCam 8000 series from Yokogawa Fluid Imaging Technologies combines the benefits of digital imaging, flow cytometry, and microscopy into a single instrument. Count and analyze tens of thousands of particles per minute and see your subvisible particles with the FlowCam s high-resolution imaging capability.
Yokogawa Fluid Imaging Technologies manufactures industry-leading particle analysis instrumentation based on digital imaging technology. Their flagship product, the FlowCam, is the first automated particle analysis instrument to use digital imaging for measuring size and shape (including 40+ morphological characteristics) of microscopic particles in a fluid medium. With applications in oceanographic research, municipal water, biopharmaceutical formulations, chemicals, oil and gas, biofuels, and many other markets, the FlowCam continues to lead the way in imaging particle analysis.