Jenea Edwards sometimes feels a twinge of sadness when she sees a little girl. There was a time when Edwards looked forward to matching mother-daughter outfits and making visits to the nail salon together. Now it’s a reminder of what could have been. With one big kick on the way
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Pitt Scientists Find Key to Viral-Bacterial Co-infection
The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host’s airways, report researchers from the University of Pittsburgh School of Medicine in a paper published today in Cell Reports.
The sacs, or “vesicles,” which carry iron bound to a protein called transferrin, associate with bacterial cells and supply them with essential nutrients, promoting the growth of expansive bacterial communities. The finding gives us a glimpse into how bacteria exploit the host’s defense system against pathogens and can offer a new way for creating therapies to prevent secondary bacterial infections in the clinical setting.