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Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.
Brain Circuit Overexcitement Tied to Autism Seizures, Deficits miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
A genetic subtype of ASD and schizophrenia have a duplicate gene that triggers overactivity in neural circuits, leading to social deficits and seizures. When researchers reduced the level of the PRRT2 gene in mouse models of 16p11.2 duplication syndrome, social behaviors were restored and seizure activity decreased.