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Regeneran partes del cráneo afectadas un defecto de nacimiento común, en ratones

Regeneran partes del cráneo afectadas un defecto de nacimiento común, en ratones
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United statesUnited kingdomYang chaiSchool herman ostrowBiology andSouthern californiaஒன்றுபட்டது மாநிலங்களில்ஒன்றுபட்டது கிஂக்டம்யாங் சாய்தெற்கு கலிஃபோர்னியா

Stem cells fix skull shape, brain function in mouse model of childhood disorder

Stem cells fix skull shape, brain function in mouse model of childhood disorder Scientists regenerate parts of the skull affected by craniosynostosis, a common birth defect Using stem cells to regenerate parts of the skull, scientists corrected skull shape and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States, according to the Centers for Disease Control and Prevention. The only current therapy is complex surgery within the first year of life, but skull defects often return afterward. The study, supported by the National Institute of Dental and Craniofacial Research (NIDCR), could pave the way for more effective and less invasive therapies for children with craniosynostosis. The findings were published Jan. 7, 2021 in

United statesLos angelesLillian shumYang chaiCenters for diseaseHerman ostrow school of dentistryNational institutes of healthDivision of extramural researchUniversity of southern californiaCraniofacial researchDisease controlNational instituteNational institutesCraniofacial molecular biologyHerman ostrow schoolSouthern california

Stem cell therapy corrects skull, brain function in mouse model of childhood disorder

E-Mail IMAGE: A stem cell-based treatment given to young mice with craniosynostosis regenerated the flexible joints between skull bones and restored skull shape and size (right), compared to untreated animals (left), as. view more Credit: Amanda Frataccia, USC Using stem cells to regenerate parts of the skull, scientists corrected skull shape and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States, according to the Centers for Disease Control and Prevention. The only current therapy is complex surgery within the first year of life, but skull defects often return afterward. The study, supported by the National Institute of Dental and Craniofacial Research (NIDCR), could pave the way for more effective and less invasive therapies for children with craniosynostosis. The findings were published Jan. 7, 2021 in

United statesLos angelesLillian shumYang chaiCenters for diseaseHerman ostrow school of dentistryUs department of healthHuman servicesNational institutes of healthUniversity of southern californiaDivision of extramural researchCraniofacial researchDisease controlNational instituteNational institutesCraniofacial molecular biology

Stem cell treatment corrects skull shape and restores brain function in mouse model of childhood disorder

Date Time Share HIN Using stem cells to regenerate parts of the skull, scientists corrected skull shape and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States, according to the Centers for Disease Control and Prevention. The only current therapy is complex surgery within the first year of life, but skull defects often return afterward. The study, supported by the National Institute of Dental and Craniofacial Research (NIDCR), could pave the way for more effective and less invasive therapies for children with craniosynostosis. The findings were published Jan. 7, 2021 in Cell. NIDCR is part of the National Institutes of Health.

United statesLos angelesLillian shumYang chaiCenters for diseaseHerman ostrow school of dentistryUs department of healthHuman servicesNational institutes of healthUniversity of southern californiaDivision of extramural researchCraniofacial researchDisease controlNational instituteNational institutesCraniofacial molecular biology

Stem cells may correct deformity and restore brain function after childhood disorder

Date Time Stem cells may correct deformity and restore brain function after childhood disorder Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States. The only current therapy is complex surgery within the first year of life, but skull defects often return afterward. The study, which appears today in Cell, could pave the way for more effective and less invasive therapies for children with craniosynostosis. “I started my career as a clinician treating kids with congenital defects, and we always wanted to do something better for these patients,” said study leader Yang Chai, a University Professor and director of the Center for Craniofacial Molecular Biology at the Herman Ostrow School of Dentistry of USC.

United statesZhen zhaoYang chaiBerislavv zlokovicRussell jacobsYingxi wuMengfei yuMark urataHuiming wangJianfu chenAxel montagneOstrow schoolHerman ostrow school of dentistryThach vu ho of the centerKeck school of medicineKey laboratory of oral biomedical research