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The elusive area postrema  Nausea is a sense of malaise that all of us know. The sensation can be so overpowering that it leads us to wonder how and why this wretched condition  happens. Researchers in Stephen Liberles’ lab at Harvard Medical School did more than wonder. They took the time and applied their expertise to study the neurons and circuits in the brain that control nausea, and reported their findings just in time for Thanksgiving.  Deep in the brainstem, on the floor of the fourth ventricle lies the area postrema.  A wide variety of evidence suggests that this region of the brain must be involved in nausea.  Importantly, there is no blood brain barrier between the cells of the area postrema and the circulating plasma, so these cells are perfectly positioned  to sample circulating poisons that most neurons would never encounter. However, the area postrema lies in a very specialized part of the brain which is very difficult to access experimentally.

United statesChuchu zhangSara prescottJudith kayeZerong caiYandan wangLiberles labMontana molecularஒன்றுபட்டது மாநிலங்களில்சுச்சு ஜாங்சாரா ப்ரெஸ்காட்ஜூடித் கேமஂட்யாந மூலக்கூறு