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Treatment Initiation With Thiazide Diuretics Increases Hyponatremia Risk

Two-year cumulative incidence of hyponatremia 2.83% for bendroflumethiazide, 3.51% for hydrochlorothiazide plus RASi

Healthday newsWorm anderssonStatens serum institut

Treatment initiation with thiazide diuretics increases hyponatremia risk, researchers find

Treatment initiation with thiazide diuretics increases hyponatremia risk, researchers find
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Worm anderssonStatens serum institutNiklas worm anderssonCumulative incidenceThiazide induced hyponatremiaInternal medicine

Treatment Initiation With Thiazide Diuretics Increases Hyponatremia Risk

Two-year cumulative incidence of hyponatremia 2.83% for bendroflumethiazide, 3.51% for hydrochlorothiazide plus RASi.

Healthday newsWorm anderssonStatens serum institut

Topical Corticosteroid Use in Pregnancy Not Tied to SGA, LBW

May 6, 2021 WEDNESDAY, May 5, 2021 (HealthDay News) Topical corticosteroid use in pregnancy is not associated with increased risks for small for gestational age (SGA) or low birth weight, according to a study published online May 5 in JAMA Dermatology. Niklas Worm Andersson, M.D., from the Statens Serum Institut in Copenhagen, Denmark, and colleagues examined whether topical corticosteroid use in pregnancy is associated with increased risks for SGA and low birth weight from a source cohort of 1.1 million pregnancies. A total of 60,497 topical corticosteroid-exposed pregnancies were identified and matched with 241,986 unexposed pregnancies on the basis of propensity scores. The researchers found that 9.4 percent of the delivered infants of pregnancies exposed to topical corticosteroids were born SGA compared with 9.4 percent among the matched unexposed pregnancies (relative risk ratio, 1.00; 95 percent confidence interval, 0.98 to 1.03). Low birth weight occurred in 3.3 and 3.

Healthday newsWorm anderssonStatens serum institutபுழு ஆண்டர்சன்

Opioid Use in Early Pregnancy Not Tied to Most Birth Defects

Feb 15, 2021 FRIDAY, Feb. 12, 2021 (HealthDay News) Opioid use in early pregnancy is associated with a small increase in risk for cleft palate but no increase in risk for most major congenital malformations, and macrolide use in pregnancy is not associated with increased risk for major birth defects in offspring, according to two studies published online Feb. 10 in The BMJ. Brian T. Bateman, M.D., from Brigham and Women’s Hospital in Boston, and colleagues examined the risks of first trimester exposure to prescription opioids for major congenital malformations. Data were included for 1,602,580 publicly insured (MAX) and 1,177,676 commercially insured (MarketScan) pregnant women, of whom 4.4 and 1.1 percent, respectively, had two or more dispensations of any opioid during the first trimester. The researchers found that the absolute risk of malformations was 41.0 versus 32.0 per 1,000 pregnancies exposed to opioids versus unexposed in the MAX cohort and 42.6 versus 37.3 per 1,0

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