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Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients
A Roswell Park Comprehensive Cancer Center team led by Christine Ambrosone, PhD, and Song Yao, PhD, has revealed a distinct molecular signature in the tumor tissues of Black patients with breast cancer.
The new work, published today in
JNCI, the Journal of the National Cancer Institute, reports that an elevated number of exhausted, nonfunctional T cells appears to be driving tumors in patients of African descent to be more aggressive and hard-to-treat -; a finding that also opens the door to treatment interventions that could help to eliminate the striking disparities in survival between Black and white patients with breast cancer.