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In the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.
A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.
A small clinical trial of postmenopausal women with prediabetes shows that the compound NMN (nicotinamide mononucleotide) improved the ability of insulin to increase glucose uptake in skeletal muscle, which often is abnormal in people with obesity, prediabetes or Type 2 diabetes. NMN also improved expression of genes that are involved in muscle structure and remodeling. However, the treatment did not lower blood glucose or blood pressur
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IMAGE: Senior investigator Samuel Klein, MD, (left), in the laboratory with Adewole Okunade, PhD. Klein s team found that NMN improved the ability of insulin to increase glucose uptake in skeletal muscle.. view more
Credit: Matt Miller
A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.
A small clinical trial of postmenopausal women with prediabetes shows that the compound NMN (nicotinamide mononucleotide) improved the ability of insulin to increase glucose uptake in skeletal muscle, which often is abnormal in people with obesity, prediabetes or Type 2 diabetes. NMN also improved expression of genes that are involved in muscle structure and remodeling. However, the treatment did not lower blood glucose or blood pressure, improve blood lipid profile, increase insulin sensitivity
January 6, 2021 SHARE Chancellor Andrew D. Martin (center) helps welcome new students and families Sept. 5 as they move in to the South 40 residence halls before the start of the fall 2020 semester. (Photo: James
Byard/Washington University)
Other than that, how was the play, Mrs. Lincoln?
Indeed, to celebrate 2020 seems absurd, even wrong and yet, perhaps necessary.
In 2020, members of the Washington University in St. Louis community made new discoveries and friendships; accomplished incredible feats in teaching and learning; welcomed amazing new students; and said goodbye to one of the greatest leaders in university history.
We hungered for this good news, as evidenced by the thousands of hits and views on our sites and social platforms. Here, Washington University shares some of its most popular and uplifting stories and videos from a year we can never forget.