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Abstract Nickel laterite ore deposits are becoming increasingly important sources of Ni for the global marketplace and are found mainly in tropical and subtropical regions, including Indonesia, the Philippines, Papua New Guinea, Cuba, and New Caledonia. There are few legislatively derived standards or guidelines for the protection of aquatic life for Ni in many of these tropical regions, and bioavailability-based environmental risk assessment (ERA) approaches for metals have mainly been developed and tested in temperate regions, such as the United States and Europe. This paper reports on a multi-institutional, 5-y testing program to evaluate Ni exposure, effects, and risk characterization in the Southeast Asia and Melanesia (SEAM) region, which includes New Caledonia, Papua New Guinea, the Philippines, and Indonesia. Further, we have developed an approach to determine if the individual components of classical ERA, including effects assessments, exposure assessments, and risk charact

New caledoniaPapua new guineaUnited statesNew caledonia generalSociety of environmental toxicology chemistryWiley periodicalsSoutheast asiaEnviron assess managIntegrated environmental assessmentEnvironmental toxicologyBioavailability based approachesEtals risk assessmentRopical risk assessmentபுதியது கலிடோனியாபப்புவா புதியது கினியாஒன்றுபட்டது மாநிலங்களில்