here on the uk, a dramatic change in economic direction the biggest tax cuts in half a century in a bid to kick start growth. more than 70 migrants die after their boat sinks off the coast of syria our correspondent is with the rescue operation. we are now at the syrian lebanese border, where some of the bodies just arrived. and a new type of cancer therapy which is showing promising results in early human trials. we speak to the study leader. hello and welcome. officials in four russian occupied regions of ukraine have been holding self declared referenda on whether to become part of the russian federation. the kremlin supports the votes just as it did after the annexation of crimea, the ukrainian territory which was invaded in 2014. but the government in kyiv and western countries have condemned the referenda, saying they are just a sham and that they will never be recognised. these are the four areas where voting is being held. they include occupied parts of luhan
cancers. so we put in genes that would simile the bodies immune system, to fight cancer, and we also put in the ability of that virus to manufacture and immunotherapy drug inside the cancer itself, so rather than having to give that drug as an injection of the virus makes it for us within the tumour, and so we treated patients with direct injections into the tumours, initially just with the verizon injections into the tumours, initiallyjust with the verizon its own, and then with the virus plus a standard immunotherapy. and in the first phase we saw dramatic responses in three of the nine patients, and in the study with immunotherapy, we saw the patients who previously had progressive disease when receiving those same therapies, a number of those patients had substantial responses of their disease, so this is encouraging data that really points the way to further trials. find encouraging data that really points the way to further trials. the way to further trials. and at this point.