Objective To determine whether a standardised and manualised care intervention in men in primary care could achieve superior improvement of lower urinary tract symptoms (LUTS) compared with usual care.
Design Cluster randomised controlled trial.
Setting 30 National Health Service general practice sites in England.
Participants Sites were randomised 1:1 to the intervention and control arms. 1077 men (≥18 years) with bothersome LUTS recruited between June 2018 and August 2019: 524 were assigned to the intervention arm (n=17 sites) and 553 were assigned to the usual care arm (n=13 sites).
Intervention Standardised information booklet developed with patient and expert input, providing guidance on conservative and lifestyle interventions for LUTS in men. After assessment of urinary symptoms (manualised element), general practice nurses and healthcare assistants or research nurses directed participants to relevant sections of the manual and provided contact over 12 weeks to assist with
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IMAGE: People with severe COVID-19 manifestations may be left with more of the protective memory T cells needed to fight reinfection. view more
Credit: La Jolla Institute for Immunology
LA JOLLA, CA A big question on people s minds these days: how long does immunity to SARS-CoV-2 last following infection?
Now a research team from La Jolla Institute for Immunology (LJI), The University of Liverpool and the University of Southampton has uncovered an interesting clue. Their new study suggests that people with severe COVID-19 cases may be left with more of the protective memory T cells needed to fight reinfection. The data from this study suggest people with severe COVID-19 cases may have stronger long-term immunity, says study co-leader LJI Professor Pandurangan Vijayanand, M.D., Ph.D.