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The initial shot should trigger the production of
antibodies to the virus for the first time. By the time we get a booster, our bodies should mount an even stronger immune response. That explains why some people have reported more side effects after their second shot.
But for people who ve already had COVID-19, the process seems to progress differently. An emerging body of research suggests that people who already got a coronavirus infection mount a stronger immune response to their first shot than those who never had the disease. That could mean that people with a history of infection don t need a second shot to sufficiently protect them from getting sick again.
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People who had Covid-19 developed at least 10 times more antibodies after their first vaccine dose than the average uninfected person who received two doses, new research shows.
Another preliminary study similarly found that healthcare workers who had Covid-19 responded to their first shot the way most people respond to their second.
The researchers both suggested that post-Covid patients may only need one shot to sufficiently protect them from the disease again.
People commonly report more side effects after their second coronavirus shot than their first.
But researchers at the Icahn School of Medicine at Mount Sinai discovered a slightly different response among patients who already had Covid-19.