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La réponse immunitaire apparaît bien plus tôt que vous ne le pensez !

La réponse immunitaire apparaît bien plus tôt que vous ne le pensez !
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Developing embryos reveal earliest immune response yet

Developing embryos reveal earliest immune response yet Appeared in BioNews 1083 The earliest signs of an innate immune response have been identified in embryos, shedding light on why some fail to form properly during early development. As reported last week in Nature, early embryos, lacking specialised immune cells, are particularly prone to cellular defects which can lead to developmental failures. Researchers at the Centre for Genomic Regulation in Barcelona, Spain, found that cells in the embryo s epithelium, the first tissue to form during vertebrate development, are able to clear surrounding dead cells, thereby increasing chances of survival, in a process known as epithelial phagocytosis .

Earliest signs of an immune response found in developing embryos

Loading video. VIDEO: An embryonic epithelial cell recognises and ingests a defective cell inside a live zebrafish embryo view more  Credit: Esteban Hoijman Researchers at the Centre for Genomic Regulation (CRG) reveal that newly formed embryos clear dying cells to maximise their chances of survival. It is the earliest display of an innate immune response found in vertebrate animals to date. The findings, which are published today in the journal Nature, may aid future efforts to understand why some embryos fail to form in the earliest stages of development, and lead to new clinical efforts in treating infertility or early miscarriages.

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