The presence of sinusitis is linked to a 40% heightened risk of a diagnosis of rheumatic disease, particularly in the 5 to 10 years before disease onset.
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Veillonella in the bacterial coating of their tongue.
Prevotella and
Veillonella are potentially pro-inflammatory bacteria, and their relative abundance suggests a possible link between oral microbes and RA.
This study builds on previous research that found that people with ERA, at risk of developing RA, and with diagnosed RA tend to experience higher rates of periodontal disease and changes in their oral and intestinal microbiota.
If confirmed, these findings could help illuminate how RA develops and improve preclinical testing for RA and ERA.
An estimated 1.5 million people living in the United States alone have RA, an autoimmune disease that causes joint pain, swelling, and eventually damage.