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Novel Subcutaneous Biologics Show Promise in AD

Patients with moderate to severe atopic dermatitis could soon have more therapeutic options, with monoclonal antibodies targeting novel immune pathways that reduce disease severity, suggest two trials.

United statesNoord hollandEric simpsonStephan weidingerTiagor matosDepartment of dermatologyEuropean academy of dermatologyKymab ltdUniversity hospital schleswig holsteinAmsterdam university medical centersOregon health science universityEuropean academyEczema areaSeverity indexOregon healthScience university

Tapinarof Effective for AD in Patients as Young as 2 years

Tapinarof cream, 1%, an aryl hydrocarbon receptor agonist, was approved in 2022 for treating plaque psoriasis in adults.

United statesJonathani silverbergEric simpsonEuropean academy of dermatologyOregon health science universityMcgovern medical schoolInterdisciplinary centerDermavant sciencesDrug administrationGeorge washington universityEuropean academyValidated investigator global assessmentOregon healthScience universityPeak pruritusNumerical rating scale

Nektar Therapeutics Reports Third Quarter 2023 Financial Results

/PRNewswire/ Nektar Therapeutics (Nasdaq: NKTR) today reported financial results for the third quarter ended September 30, 2023. Cash and investments in.

United statesSan franciscoVivian wuDavid rosenCellular biomedicine group incCellular biomedicine groupNektar therapeuticsEuropean academy of dermatologyExchange commission onDuke cancer instituteRecent businessDuke cancerEczema areaSeverity indexValidated investigator global assessmentBody surface area

Recombinant IL-2 Shows Potential in Atopic Dermatitis

"This is the first study to demonstrate the therapeutic potential of rezpegaldesleukin," said Jonathan Silverberg, MD, PhD, MPH, who presented results of a phase 1b study.

United statesNoord hollandReis matosJonathan silverbergEli lillyHealth scienceAmsterdam university medical centersGeorge washington university school of medicineEuropean academy of dermatologyNektar therapeuticsEuropean academyEczema areaSeverity indexBody surface areaGeorge washington university schoolMedscape medical news

Nektar Presents New Responder Data for Rezpegaldesleukin, a First-in-Class Selective Regulatory T-cell Therapy, in Late-Breaking News Oral Presentation at 2023 EADV Congress

Nektar Presents New Responder Data for Rezpegaldesleukin, a First-in-Class Selective Regulatory T-cell Therapy, in Late-Breaking News Oral Presentation at 2023 EADV Congress
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United statesSan franciscoJonathan silverbergVivian wuJonathan zalevskyDavid rosenNektar therapeuticsGeorge washington university school of medicineExchange commissionResearch developmentClinical researchEuropean academy of dermatologyHealth sciencesRapid onsetContinuing benefitWeek treatment period