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High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

Therapeutic-dose anticoagulation may improve COVID-19 outcomes for noncritical inpatients

NEW ORLEANS — A therapeutic vs. prophylactic dose of anticoagulation therapy did not significantly improve outcomes for noncritically ill patients hospitalized with COVID-19, though fewer therapeutic dose-treated patients died at 30 days.The FREEDOM COVID trial ultimately did not meet its primary endpoint — a 30-day composite of all-cause mortality, ICU admission, systemic

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

Giving noncritically ill patients hospitalized for COVID-19 a higher dose of blood-thinning medication than usual did not significantly reduce the combined risk of death from any cause, need for treatment in an intensive-care unit, a confirmed blood clot or a stroke at 30 days, according to the results of the FREEDOM-COVID trial presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

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