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The FINANCIAL - Human challenge trial launches to study immune response to COVID-19

Share This The FINANCIAL Though the COVID-19 pandemic has now been active for a year, not much is known about what happens when people who have already had COVID-19 are infected for a second time, Oxford University notes. Researchers at the University of Oxford have launched a human challenge trial to look at what kind of immune response can stop people from becoming re-infected. They also want to see how the immune system reacts second time round. A human challenge trial in medical research is a carefully controlled study that involves purposefully infecting a subject with a pathogen or bug, in order to study the effects of that infection.

Adults to be reinfected to study immune response in UK Covid-19 human challenge trial

They will then be able to understand what kind of immune responses protect against re-infection. They will also measure the immune response at several time points after infection to understand what immune response is generated by the virus. “A challenge study allows us to make these measurements very precisely because we know exactly when someone is infected. The information from this work will allow us to design better vaccines and treatments, and also to understand if people are protected after having Covid, and for how long,” said McShane, adding that it would also help with designing tests that can more accurately predict whether people are protected.

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