This paper presents a hybrid mutual coupling reduction technique applied onto a dual-band textile MIMO antenna for wireless body area network and 5G applications. The MIMO antenna consists of two hexagonal patch antennas, each integrated with a split-ring (SR) and a bar slot to operate in dual-band mode at 2.45 GHz and 3.5 GHz. Each patch is dimensioned at 47.2 × 31 mm2. This hybrid technique results in a simple structure, while enabling significant reduction of mutual coupling (MC) between the closely spaced patches (up to 0.1 λ). This technique combines a line patch and a patch rotation technique, explained as follows. First, a line patch is introduced at an optimized distance to enable operation with a broad impedance bandwidth at both target frequencies. One of the patches is then rotated by 90° at an optimized distance, resulting in a significant MC suppression while maintaining the dual and broad impedance bandwidth. The proposed MIMO antenna is further evaluated under several