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<p style="text-align:justify">Tokyo, Japan &ndash; Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies. For the first time, they showed that the &ldquo;proofreading&rdquo; portion of the DNA replicating enzyme polymerase epsilon ensured safe termination of replication at damaged portions of the DNA strand, ultimately saving DNA from severe damage. This new knowledge arms scientists with ways to make anti-cancer drugs more effective, and new diagnostic methods.</p>

Pearl riverKouji hirataYamada science foundationResearch networksTokyo metropolitan government advanced research grantTakeda science foundationShenzhen universityNagasaki universityFukushima medical universityTokyo metropolitan government advanced research grant numberKanae foundationNucleic acids researchRadiation disaster medical science of hiroshima universityNational natural science foundation of chinaUehara memorial foundationTokyo metropolitan university