In 2020, Passage Bio , a genetic medicines company focused on rare disorders of the central nervous system, boasted a workforce of 20. That number has jumped to 100, with the aim of reaching 150 this year, according to CEO Bruce Goldsmith . The Center City-based company’s quick expansion signals the uptick in employment opportunities and economic growth among the three dozen cell therapy, gene therapy , and gene editing companies located across the Philadelphia region. Last year, the Philadelphia region’s entire life sciences hub ranked sixth in the United States, according to the JLL 2020 U.S. Life Sciences Real Estate Outlook , which tracks trends in the field, based on “new peaks in capital venture investment and life sciences employment.”