Scientists unravel how cell death is initiated on a molecular level
The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors. Mitochondria, the power plants of cells, play a role in this programmed cell death. Scientists from the University of Groningen (the Netherlands) and the University of Pittsburgh (U.S.) have obtained new insights in how mitochondria receive the signal to self-destruct. Their results were published in the
Journal of Molecular Biology.
How does a cell kill itself? The details of this process are still unclear. Patrick van der Wel, associate professor of Solid-State NMR Spectroscopy at the University of Groningen, is working together with colleagues at the University of Pittsburgh to see how cell death is initiated on a molecular level. The membranes of mitochondria play a key role , he explains. Cardiolipin, a special type of membrane lipid, acts as an important signal. If it g
How an Unfolding Protein Can Induce Programmed Cell Death
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How an unfolding protein can induce programmed cell death
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