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Antibacterial substance from staphylococci discovered with new mechanism of action against natural competitors

Antibacterial substance from staphylococci discovered with new mechanism of action against natural competitors
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Baden wübergNordrhein westfalenUnited kingdomFabian greinTanja schneiderWeitere informationenWissenschaftliche ansprechpartnerWissenschaftliche publikationenDominik brajtenbachUlrich kubitscheckGerman research foundationGerman centerLife healthUniversity of bonnInstitute of pharmaceutical microbiologyBonn university hospital

Breakthrough in brown fat research: Researchers have found brown fat s off-switch

Breakthrough in brown fat research: Researchers have found brown fat s off-switch
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Nordrhein westfalenHande topelRonja kardinalDagmar wachtenJan wilhelm kornfeldLife healthCollaborative research center transregioNovo nordisk centerUniversity of bonn germanyUniversity of bonnInstitute of innate immunityNovo nordisk foundation centerUniversity of southern denmarkUniversity hospital bonnEnergy balance batenergyTransdisciplinary research areas

Bacteria Produce Potential Antibiotic Alternative

Bacteria Produce Potential Antibiotic Alternative
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Nordrhein westfalenTanja schneiderFabian greinUlrich kubitscheckInstitute of pharmaceutical microbiologyLife healthGerman centerUniversity hospital bonnGerman research foundationUniversity of bonnInfection researchTransdisciplinary research areaPharmaceutical microbiologyBiophysical chemistryJan samuel pulsThomas flie

Possible alternative to antibiotics produced

<p><strong>Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment. Researchers at the University Hospital Bonn (UKB), the University of Bonn and the German Center for Infection Research (DZIF) have discovered a new so-called lantibiotic, namely epilancin A37. It is produced by staphylococci that colonize the skin and acts specifically against their main competitors there, the corynebacteria. This specificity is presumably mediated by a very special mechanism of action, which the researchers were able to decipher in detail. Their results have now been published in the renowned ISME Journal.</strong></p>

Nordrhein westfalenTanja schneiderUlrich kubitscheckFabian greinUniversity hospital bonnGerman centerTransdisciplinary research areaGerman research foundationUniversity of bonnLife healthInfection researchInstitute of pharmaceutical microbiologyPharmaceutical microbiologyBiophysical chemistryJan samuel pulsThomas flie

Simplified diagnosis of rare eye diseases

Simplified diagnosis of rare eye diseases
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Nordrhein westfalenBaden wübergMaximilian wintergerstMatthias mauschitzUniversity hospital bonnUniversity of bonnEye clinicUveitis clinic