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U-M researchers target a protein channel in the cell s lysosome to selectively kill cancer cells

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body.

To selectively kill cancer cells, target protein channel in cell s lysosome

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity

Sleep loss sabotages new memory storage in the hippocampus -- Science of the Spirit -- Sott net

© Frank Raven Somatostatin-expressing interneurons in the mouse dentate gyrus, labeled with Brainbow 3.0, which labels each neuron a distinct color. cFos, labeled green, is present in the nuclei of surrounding pyramidal cells which are active during sleep. I While some students may think it s a good idea to pull an all-nighter before an exam, conventional wisdom may be correct: A good night s sleep may actually be more helpful, according to University of Michigan research. U-M scientists Sara Aton and James Delorme found when mice are sleep-deprived, there is an increase in activity in inhibitory neurons in the hippocampus, an area of the brain essential for navigation, as well as for processing and storing new memories.

Sleep is vital to associating emotion with memory, according to U-M study

When you slip into sleep, it’s easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain. U-M researchers have been studying how memories associated with a specific sensory event are formed and stored in mice. In a study conducted prior to the coronavirus pandemic and recently published in Nature Communications, the researchers examined how a fearful memory formed in relation to a specific visual stimulus. They found that not only did the neurons activated by the visual stimulus keep more active during subsequent sleep, sleep is vital to their ability to connect the fear memory to the sensory event.

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows When you slip into sleep, it s easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain. U-M researchers have been studying how memories associated with a specific sensory event are formed and stored in mice. In a study conducted prior to the coronavirus pandemic and recently published in Nature Communications, the researchers examined how a fearful memory formed in relation to a specific visual stimulus. They found that not only did the neurons activated by the visual stimulus keep more active during subsequent sleep, sleep is vital to their ability to connect the fear memory to the sensory event.

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