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ADC With Radiotherapy for Brain Mets Ups Risk of Necrosis

An antibody-drug conjugate given concurrently with stereotactic radiotherapy to treat brain metastases may increase patients risk for symptomatic radiation necrosis, a study suggests.

New-york
United-states
Memorial-sloan-kettering-cancer-center
Emilys-lebow
Malignant-head-and-neck-neoplasm
Brain-metastasis
Metastatic-brain-tumor
Radiosurgery
Tereotactic-radiotherapy
Radiation-oncology
Brain

Trial Shows Precision Medicine in RA 'Remains Elusive'

Histologic analysis did not sufficiently predict treatment response to certain medications, but methods involving gene expression and transcriptome analysis may be more promising.

Minnesota
United-states
Chicago
Illinois
University-medical-center
Netherlands
United-kingdom
Mayo-clinic-in-rochester
Elena-myasoedova
Harrisr-perlman
Costantino-pitzalis
Queen-mary-university-of-london

Investigational ADC Improves PFS in Metastatic Breast Cancer

Datopotamab deruxtecan led to better progression-free survival and safety compared with standard chemotherapy in patients with metastatic HER-2 negative breast cancer.

Boston
Massachusetts
United-states
New-york
Memorial-sloan-kettering-cancer-center
Sarat-chandarlapaty
Aditya-bardia
Cancer-center
European-society-for-medical-oncology-congress
Mass-general-cancer-center
Medical-oncology
Metastatic-breast-carcinoma

UCSF's Dr Stephen Hauser Sketches MS Future

A neurology professor talks about the need to identify early biomarkers of MS, describes a three-stage model for the disease, and ponders how to define cure in this setting.

Milan
Lombardia
Italy
San-francisco
California
United-states
Stephen-hauser
Drug-administration
Us-department-of-defense
University-of-california
Novartis
Multiple-sclerosis-ms

Takeda Announces Voluntary Withdrawal of Lung Cancer Therapy

The company said on Monday it will voluntarily withdraw its lung cancer therapy from the US after it failed to meet the main goal in a late-stage study.

Australia
China
United-states
Bengaluru
Karnataka
India
South-korea
Switzerland
Takeda-exkivity
Sriparna-roy
Shilpi-majumdar
Shinjini-ganguli

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