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New Treatment Targets Specific Protein Regions in Medulloblastoma

New Treatment Targets Specific Protein Regions in Medulloblastoma
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Ernst schonbrunnBrent orrMatthew reesLogan siguaMartine rousselAudrey mercierIan delahuntyYingzhe wangNoha shendyQi liuMelissa ronanMustafa kocakAdam durbinSarah robinsonJun qiJennifer roth

Targeting specific protein regions offers a new treatment approach in medulloblastoma

Targeting specific protein regions offers a new treatment approach in medulloblastoma
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Mustafa kocakJun qiMatthew reesBrent orrMelissa ronanYang zhangLogan siguaYousef khashanaAdam durbinYingzhe wangBurgess freemanMartine rousselNohaam shendyErnst schonbrunnMelissa bikowitzSarah robinson

Targeting specific protein regions offers a new treatment approach in medulloblastoma

Explore how research targeting EP300/CBP protein in Group 3 medulloblastoma may advance targeted pediatric brain tumor treatments by inhibiting bromodomains.

Sarah robinsonJennifer rothAudrey mercierQi liuTingjian wangBrian abrahamIan delahuntyNoha shendyVanshita goelMelissa ronanYang zhangBrent orrMustafa kocakJun qiMatthew reesYousef khashana

Targeting specific protein regions offers a new treatment approach in medulloblastoma

Explore how research targeting EP300/CBP protein in Group 3 medulloblastoma may advance targeted pediatric brain tumor treatments by inhibiting bromodomains.

Sarah robinsonAudrey mercierJennifer rothQi liuTingjian wangBrian abrahamIan delahuntyNoha shendyVanshita goelYang zhangMelissa ronanBrent orrMatthew reesJun qiMustafa kocakYousef khashana

Brain mimetic co-culture reveals new targets in lung cancer brain metastases

Researchers at Kanazawa University, Japan, have reported a mixed-glial culture on/in soft substrate (MGS) platform to investigate cancer-glia interactions in vitro. Using this model, they showed that astrocytes favored brain metastasis by promoting metabotropic glutamate mGlu1 receptor (mGluR1) expression in cancer cells and stabilizing EGFR. Eishu Hirata, an associate professor at the Cancer Research Institute, Division of Tumor Cell Biology and Bioimaging at Kanazawa University, and his team published their work on Feb. 2, 2024, in Developmental Cell.

Eishu hirataDivision of tumor cell biologyResearchers at kanazawa universityCancer research instituteKanazawa universityTumor cell biologyBioworld scienceNon small cell lung cancerBrain metastasesLy 456236Co cultureMglu1 receptor