Author summary Why was this study done? Developing new and innovative interventions to improve tuberculosis (TB) care services use and successful treatment are essential to the global efforts to end TB. There is a limited scope on the overall impact of these interventions because most studies focus on interventions’ capacity to enhance specific TB care outcomes. Evaluating existing evidence to ascertain the effect TB interventions on overall care cascade outcomes is paramount to informing holistic TB control strategies What did the researchers do and find? We systematically reviewed and meta-analyzed evidence on TB interventions and their effects on the TB care cascade for active TB from 144 peer-reviewed studies. In this study, the 5 out of 12 identified TB interventions associated with multiple care cascade outcomes were education and counseling, incentives, digital interventions, community-based, multisector collaborations, and mixed interventions. Among LMIC studies, ed
Placide Nsengiyumva and colleagues analyze costs and cost-effectiveness of scaling up target regimens for Tuberculosis Preventive Treatment among persons living with HIV and household contacts of TB patients in Brazil and South Africa.