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Squeegee Helps To Detect Contamination in Low Microbial Biomass Microbiomes

Researchers developed a new contamination detection tool to establish reproducibility in the identification and analysis of microbiomes in challenging, low abundance samples.

Meet Squeegee: A new contamination detection tool for low microbial biomass microbiomes

Bioinformatics tool accurately tracks synthetic DNA

 E-Mail IMAGE: The Rice University computer science lab of Todd Treangen challenged and beat deep learning in a test to see if a new bioinformatics approach effectively tracks the lab. view more  Credit: Tommy LaVergne/Rice University HOUSTON - (Feb. 26, 2021) - Tracking the origin of synthetic genetic code has never been simple, but it can be done through bioinformatic or, increasingly, deep learning computational approaches. Though the latter gets the lion s share of attention, new research by computer scientist Todd Treangen of Rice University s Brown School of Engineering is focused on whether sequence alignment and pan-genome-based methods can outperform recent deep learning approaches in this area.

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