to give boosters at the moment. the covid case surge the biggest test yet for the biden administration. we re unvaccinated. we are looking at a winter of severe illness and death. why the vice president says the white house didn t see these variants coming. meantime, spiking cases forcing holiday shows to shutter and upending the return of live pro sports. i believe we re facing major c cancellations. tonight the country s top covid advisers reminding america that science can and will save us. we have the tools to do it, but we need the american people to do their part, to protect themselves. we will win this war with this virus. i m pamela brown in washington. you re in the cnn newsroom. and tonight america on alert in the face of an alarming new