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Astrocyte Study Ties Vitamin B12 to Multiple Sclerosis Progression

A new study uncovers a molecular connection between vitamin B12 and multiple sclerosis (MS).

Mochida
Miyazaki
Japan
New-york
United-states
Tokyo
Tomomi-furihata
Yasuyuki-kihara
Jerold-chun
Richard-rivera
Manisha-ray
Deepa-jonnalagadda

Link Discovered Between Vitamin B12 Loss, Multiple Sclerosis

Link Discovered Between Vitamin B12 Loss, Multiple Sclerosis
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

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Japan
Mochida
Miyazaki
New-york
United-states
Jerold-chun
Deepa-jonnalagadda
Manisha-ray
Arjun-saha
Richard-rivera
Clayton-ellington

Intracranial Intrigue: Unmasking the Mutant Genes Behind Brain Aneurysms

Researchers at the RIKEN Center for Brain Science (CBS) in Japan have discovered a set of related mutations that lead to intracranial aneurysms weakened blood vessels in the brain that can burst at any time. The mutations all appear to act on the same biological signaling pathway, and the researcher

Japan
Xiaoning-sun
Masato-nakafuku
Motoo-nagane
Atsuko-nakanishi-ozeki
Nobuhito-saito
Tadafumi-kato
Hiroyasu-kamiyama
Masashi-fujita
Rokuya-tanikawa
Nakao-ota
Shigeo-okabe

Stroke of Luck: Therapeutic Target Discovered in Blood–Brain Barrier

  Scientists from Japan and the United States have identified a new mechanism of blood-brain barrier degradation in the post-stroke brain, involving acrolein-induced modifications of proheparanase. This discovery could lead to the production of newer and more effective drugs for stroke-related disorders. Credit: Toubibe from Pixabay Read Time: The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation. Now, for the first time, researchers have identified how a toxic stroke byproduct, acrolein, could activate the barrier-degrading enzyme proheparanase (proHPSE). The research group has discovered that proHPSE degrades the glycocalyx within the post-stroke brain s blood vessels, providing hope for new and effective therapeutics against post-stroke inflammation.

Japan
Tokyo
United-states
Kazuei-igarashi
Tomomi-furihata
Takehiro-suzuki
Toshihiko-toida
Kyohei-higashi
Naoshi-dohmae
Robertj-linhardt
Tokyo-university-of-pharmacy
Amine-pharma-research-institute

Study reveals a potential target for stroke treatment in blood-brain barrier

Study reveals a potential target for stroke treatment in blood-brain barrier
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

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Tokyo
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Takehiro-suzuki
Naoshi-dohmae
Emily-henderson
Tomomi-furihata
Kazuei-igarashi
Kyohei-higashi
Toshihiko-toida
Robertj-linhardt
Tokyo-university-of-pharmacy
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