Sotatercept with background therapy significantly improved exercise capacity and multiple secondary outcome measures compared to background therapy alone in the STELLAR trial.
Bempedoic acid and bempedoic–ezetimibe are now indicated to prevent myocardial infarction and cardiovascular procedures in both primary- and secondary-prevention patients regardless of statin use.
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New data on the timing of CSF biomarker changes leading to a diagnosis of Alzheimer's disease could provide useful starting points for prevention and therapeutic strategies.
The European Medicines Agency has validated a Marketing Authorization Application seeking the approval of nirogacestat for patients with desmoid tumors.