suspect with a long gun, possibly from a rooftop in new jersey. the urgent manhunt tonight. the midterm elections just one week away. president biden campaigning in florida, where democrats are in an uphill battle. new hope of preventing rsv, the virus overwhelming children s hospitals as pfizer announces the results of its vaccine trials. after her disqualification sparked outrage, the young athlete inspiring america, by taking on her biggest race yet. announcer: this is nbc nightly news with lester holt. good evening. not guilty was the plea late today from the bay area man accused of beating paul pelosi with a hammer inside his san francisco home last week. david depape making his first court appearance on state charges today after his own words offered insight into his possible state of mind and alleged intentions, that authorities say were aimed at house speaker nancy pelosi. tonight an online trail suggesting depape was drawn to conspiracy theories. the stat