Aptose Expands Senior Leadership Team
Aptose Biosciences Inc. a clinical stage company developing highly differentiated therapeutics that target the underlying mechanisms of cancer, today announced the appointment of two key members to its management team to support the company’s expanding clinical CMC and regulatory functions: George P. Melko, Pharm.D., joins Aptose as Vice President, Regulatory Affairs; and Robert B. Killion Jr., Ph.D. has been … George Melko, Pharm.D. joins as Vice President, Regulatory Affairs Robert Killion, Ph.D. appointed Vice President, CMC
Aptose Biosciences Inc. (Nasdaq: APTO; TSX: APS), a clinical stage company developing highly differentiated therapeutics that target the underlying mechanisms of cancer, today announced the appointment of two key members to its management team to support the company’s expanding clinical CMC and regulatory functions: George P. Melko, Pharm.D., joins Aptose as Vice President, Regulatory Affairs; and Robert B.
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IMAGE: Matthew Foster, MD, and his UNC Lineberger colleagues have used an experimental safety switch incorporated as part of a chimeric antigen receptor-modified T cell therapy (CAR-T) for an aggressive form. view more
Credit: UNC Lineberger Comprehensive Cancer Center
CHAPEL HILL, North Carolina UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur. This advance was seen in a patient enrolled in a clinical trial using CAR-T to treat refractory acute B-cell leukemia. It demonstrates a proof-of-principle for possible expanded use of CAR-T immunotherapy paired with the safety switch.
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BEDMINSTER, N.J. and SINGAPORE, Jan. 18, 2021 /PRNewswire/
Tessa Therapeutics (Tessa), a clinical-stage cell therapy company developing next-generation cancer treatments for hematological malignancies and solid tumors, today announced that the European Medicines Agency (EMA) has granted PRiority MEdicines (PRIME) designation to the company s lead autologous CD30 CAR-T therapy for the treatment of relapsed or refractory classical Hodgkin Lymphoma (R/R cHL).
PRIME is a program launched by EMA to optimize development plans and speed up evaluation of medicines that demonstrate major therapeutic advantage over existing treatments, or otherwise benefit patients without treatment options. Through this program, EMA offers enhanced support to medicine developers including early interaction and dialogue, and a pathway for accelerated evaluation by the agency.
5 Questions With… 2020 Recap
In 2020 we introduced a new series titled “5 Questions With…” in an effort to spotlight individuals from across the BioHealth Capital Region and beyond. Providing this platform has allowed us to help share the stories of industry peers and show that there isn’t a single “right” way to becoming an industry success.
As the year wraps up and we look forward to 2021, we are also looking back to the 30 guests we’ve featured in this series. From CFOs to Scientists, Veterans to Venture Capitalists, Company Founders to Leadership who recently joined their current companies, and everyone inbetween.
3T Biosciences Appoints Industry Veteran John Connolly as Interim CEO
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SOUTH SAN FRANCISCO, Calif., Dec. 16, 2020 /PRNewswire/ 3T Biosciences, an immunotherapy company, today announced that John Connolly, Ph.D. has been appointed as interim CEO. Together with the current leadership team, Dr. Connolly will lead the next round of financing with an emphasis on leveraging the company s 3T-TRACE™ technology for novel target discovery and therapeutic development.
John Connolly, Interim CEO, 3T Biosciences John has vast experience building and leading research and clinical programs in cell and gene therapy. It s an honor to have him guiding our program as we advance this business to the next phase of its evolution. Given his past and current experience, John has a successful track record of helping to raise capital and collaborating with innovative biopharmaceutical companies across the globe, stated Hanspeter Gerber, Ph.D.,