It's gone from an idea widely mocked on Capitol Hill to one that enjoyed broad bipartisan support as part of the recently passed defense spending bill and its supporters believe the change in attitude will save lives in the real world.
As psychedelic therapy trials get bigger and the drugs become more accessible, researchers need to start talking about their potential adverse effects.
Most psychedelic advocates picture a future where the drug war is over and people are free to use a number of currently illicit substances but exactly how we get to that utopian future is the source of great acrimony in a previously unified community.