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Datopotamab Deruxtecan Biologics License Application Accepted in the U S for Patients with Previously Treated Advanced Nonsquamous Non-Small Cell Lung Cancer

Application based on results from the TROPION-Lung01 phase 3 trial If approved, Daiichi Sankyo and AstraZeneca’s datopotamab deruxtecan may be the first TROP2 directed antibody drug conjugate.

United statesKen takeshitaSusan galbraithAnn oncDaiichi sankyoDrug administrationEuropean society for medical oncologyAnticancer researchAmerican cancer societyNational cancer instituteMerck co incSapporo medical universityBiologics license applicationPrescription drug user fee actPresidential symposiumEuropean society

Datopotamab deruxtecan Biologics License Application accepted in the US for patients with previously treated advanced nonsquamous non-small cell lung cancer

Application based on results from the TROPION-Lung01 Phase III trial If approved, AstraZeneca and Daiichi Sankyo’s datopotamab deruxtecan may be the first TROP2-directed antibody drug conjugate.

United statesUnited kingdomAnn oncDaiichi sankyo biologicsDaiichi sankyoSusan galbraithKen takeshitaSapporo medical universityAnticancer researchDrug administrationLung ambition allianceAmerican cancer societyEuropean society for medical oncology congressNational cancer instituteBiologics license applicationPrescription drug user fee act

Datopotamab Deruxtecan Improved Progression-Free Survival Versus Chemotherapy in Patients with Previously Treated Non-Small Cell Lung Cancer in TROPION-Lung01 Phase 3 Trial

TOKYO & BASKING RIDGE, N.J. (BUSINESS WIRE) Oct 23, 2023

United statesSusan galbraithAaron lisbergDaiichi sankyoJennifer brennanDatopotamab deruxtecanAnn oncKoji ogiwaraKen takeshitaAnticancer researchDaiichi sankyo co ltdWorld health organizationSapporo medical universityDaiichi sankyo incEuropean society for medical oncologyNational cancer institute

Datopotamab deruxtecan improved progression-free survival vs chemotherapy in patients with previously treated non-small cell lung cancer in TROPION-Lung01 Phase III trial

AstraZeneca and Daiichi Sankyo’s datopotamab deruxtecan reduced the risk of disease progression or death by 25% in overall population and by 37% in patients with non-squamous tumors Datopotamab.

United statesUnited kingdomSusan galbraithAaron lisbergDaiichi sankyoKen takeshitaAnn oncSapporo medical universityAmerican cancer societyInternational agency for research on cancerWorld health organizationNational cancer instituteLung ambition allianceEuropean society for medical oncologyAnticancer researchCongress on

Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial

Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial
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Siteman cancer centerUnited statesWashington universityMark rutsteinDaiichi sankyoJennifer brennanAnn oncSaiama waqarCristian massacesiKoji ogiwaraSapporo medical universityWashington university school of medicineInternational agency for research on cancerDaiichi sankyo incOncology clinical developmentWorld health organization