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Bioinformatics Defines Semi-Extractable RNAs across Cell Lines

Bioinformatics Defines Semi-Extractable RNAs across Cell Lines
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Chao zengMichiaki hamadaTetsuro hiroseTakeshi chujoOsaka universityNucleic acids researchKumamoto universityWaseda universityNucleic acids

Bioinformatics Defines Semi-Extractable RNAs across Cell Lines

Takeshi chujoChao zengMichiaki hamadaTetsuro hiroseWaseda universityOsaka universityKumamoto universityNucleic acids researchNucleic acids

Scientists Unveil Breakthrough in Human Cell RNAs Understanding

Scientists Unveil Breakthrough in Human Cell RNAs Understanding
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Michiaki hamadaTakeshi chujoTetsuro hiroseChao zengTransdisciplinary research initiativesSociety of japanFaculty of life sciencesUnited nationsNational institute of advanced industrial scienceInstitute forOsaka universitySustainable development goals sdgsSchool of medicineSchool of frontier biosciencesNucleic acids research onJapanese society for bioinformatics jsbi

Unraveling the mystery of semi-extractable RNAs from human cell lines

Unraveling the mystery of semi-extractable RNAs from human cell lines
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Tetsuro hiroseChao zengMichiaki hamadaTakeshi chujoNucleic acids research onKumamoto universityOsaka universityWaseda universityNucleic acids researchNucleic acids

Unraveling the mystery of semi-extractable RN

Membraneless organelles in cells contain high concentrations of semi-extractable RNAs, which could serve as potential biomarkers and drug targets. However, the identification and characterization of these RNAs have been limited. Japanese researchers have now developed a novel bioinformatic pipeline to define and analyze semi-extractable RNAs, which has led to the identification of over 1000 RNAs involved in membraneless organelle formation. This study paves the way for future investigations into RNA-centric phase separations.

Takeshi chujoMichiaki hamadaChao zengTetsuro hiroseNucleic acids researchBioinformatics laboratoryUniversity computational bio bigData open innovation laboratoryOsaka universityNippon medical schoolSustainable development goals sdgsMolecular biology society of japanInstitute forFaculty of life sciencesKumamoto universityTransdisciplinary research initiatives