The formation of aggregates due to protein misfolding and resulting protein instability is associated with several diseases. Previous studies have shown the potential of sulfobetaine polymer, a zwitterionic polymer, to suppress protein aggregation. Now, researchers elucidate the mechanism underlying this process and show ways to optimize protein stabilization using these polymers. Going ahead, future therapies may be able to prevent or reverse diseases like Alzheimer s by building on the unique ability of zwitterionic polymers.
Understanding how zwitterionic polymers can lead to safer drugs and disease prevention phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).