Objective To estimate the risk of all cause and cause specific mortality in people with obsessive-compulsive disorder (OCD) compared with matched unaffected people from the general population and with their unaffected siblings.
Design Population based matched cohort and sibling cohort study.
Setting Register linkage in Sweden.
Participants Population based cohort including 61 378 people with OCD and 613 780 unaffected people matched (1:10) on sex, birth year, and county of residence; sibling cohort consisting of 34 085 people with OCD and 47 874 unaffected full siblings. Cohorts were followed up for a median time of 8.1 years during the period from 1 January 1973 to 31 December 2020.
Main outcome measures All cause and cause specific mortality.
Results 4787 people with OCD and 30 619 unaffected people died during the study period (crude mortality rate 8.1 and 5.1 per 1000 person years, respectively). In stratified Cox proportional hazards models adjusted for birth year,
In this large population based cohort study, Qianwei Liu and co-workers explore how a diagnosis of cancer in children influences suicide risk in parents.
Even though both the absolute and relative risk of AF-related ischemic stroke declined
over the past 20 years, every fourth ischemic stroke in 2020 still had a preceding
or concurrent AF diagnosis. This represents a great potential for future gains in
stroke prevention among AF patients.
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