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Liver Transplant in CRC: Who Might Benefit?

Transplant improves survival for certain patients with colorectal cancer liver metastases

Transplant improves survival for certain patients with colorectal cancer liver metastases
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Transplant May Be Reasonable for Certain CRC Patients With Liver Mets

Study Results Raise Possibility of Liver Transplant as Tx Option for Advanced CRC Liver Metastasis

Apr 2, 2021 Increased overall survival compared with portal vein embolization, liver resection In a highly select group of patients with colorectal cancer and nonresectable liver metastases, high liver tumor load, and left-sided primary tumors, liver transplant brought about significantly higher overall survival (OS) rates compared with portal vein embolization (PVE) and liver resection. Thus, liver transplant may be a viable treatment option in future prospective studies of select patients with colorectal liver metastasis, researchers reported. Although liver resection is the standard of care in patients with colorectal cancer and liver metastasis, few patients qualify as candidates, according to researchers led by Svein Dueland, MD, PhD, of Oslo University Hospital, Norway, who had previously demonstrated significant differences in OS after liver transplant in patients with primary tumors located in the ascending colon compared with those with primary tumors in the rest of the c

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