New research findings may help physicians and older adults with osteoporosis better manage their hip fracture risk while taking a break from their medication. The first-of-its-kind study, published in the Annals of Internal Medicine, found that the oral bisphosphonates risedronate and alendronate equally protect against hip fracture during a 2-year drug holiday.
Risedronate confers less hip fracture protection than alendronate during drug holidays beyond 2 years, so a 2- to 3-year drug holiday for risedronate is likely too long.
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