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Evusheld significantly prevented COVID-19 disease progression or death in TACKLE Phase III treatment trial

Detailed results from the TACKLE Phase III outpatient treatment trial showed AstraZeneca’s Evusheld (tixagevimab and cilgavimab, formerly AZD7442) provided clinically and statistically significant protection against progression to severe COVID-19 or death from any cause compared to placebo, with treatment with .

United kingdomUnited statesGreat britainNat microbiolTixagevimab cilgavimabHugh montgomeryCompany on twitterVanderbilt university medical centerDepartment of defenseDepartment of healthEuropean unionNuclear defenseUniversity of oxfordBiomedical advanced researchHuman servicesDrug administration

EVUSHELD long-acting antibody combination retains neutralizing activity against Omicron variants BA 4 and BA 5, according to new study from University of Oxford

EVUSHELD long-acting antibody combination retains neutralizing activity against Omicron variants BA 4 and BA 5, according to new study from University of Oxford
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United kingdomGreat britainJillian gonzalesNat microbiolTixagevimab cilgavimabBrendan mcevoyJohnl perezVanderbilt university medical centerDepartment of defenseVector engineering labDepartment of healthEuropean unionNuclear defenseEuropean society of clinical microbiologyCenters for diseaseHead of late development

Tiny shark-derived antibodies broadly neutralize most SARS-CoV-2 variants

Resarchers discuss the ability of shark-derived antibodies to protect against multiple variants of SARS-CoV-2.

Sergeuwphoto shutterstockSmall methodsstudyShark derived single domain antibodiesBroadly neutralizeRelated coronavirusesStructural basisImage creditMiddle eastCoronavirus disease covid 19Covid 19N vivoArs cov 2Evere acute respiratoryEvere acute respiratory syndromeSpike proteinWeight loss

Evusheld significantly protected against symptomatic COVID-19 for at least six months in PROVENT Phase III trial in high-risk populations | Antibodies

Evusheld significantly protected against symptomatic COVID-19 for at least six months in PROVENT Phase III trial in high-risk populations

United kingdomUnited statesCity ofGreat britainAstrazeneca evusheldMyronj levinVanderbilt university medical centerDepartment of defenseCompany on twitter astrazenecaDepartment of healthUniversity of colorado school medicineEuropean unionNuclear defenseCenters for diseaseEuropean congressBiomedical advanced research

Evusheld significantly protected against symptomatic COVID-19 for at least six months in PROVENT Phase III trial in high-risk populations

Detailed results from the PROVENT Phase III pre-exposure prophylaxis (prevention) trial showed that AstraZeneca’s Evusheld (tixagevimab and cilgavimab), formerly AZD7442, reduced the risk of developing symptomatic COVID-19 by 77% in the primary analysis and by 83% in the six month follow-up analysis, compared to .

United statesUnited kingdomGreat britainMyronj levinCompany on twitterVanderbilt university medical centerDepartment of defenseDepartment of healthUniversity of colorado school medicineEuropean unionNuclear defenseCenters for diseaseEuropean congressBiomedical advanced researchHuman servicesWorld health organization