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Cancer Prevention Strategies Linked to Mortality Reduction in BRCA Carriers

Kallah Teachers, BRCA Genes, and a Tweak that Could Save Lives – The Yeshiva World

Kallah Teachers, BRCA Genes, and a Tweak that Could Save Lives – The Yeshiva World
theyeshivaworld.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from theyeshivaworld.com Daily Mail and Mail on Sunday newspapers.

Not Just BRCA: Large Studies ID Other Key Breast Cancer Risk Genes

email article Two large breast cancer case-control studies of women from the United States, Europe, and Asia identified eight genes that had significant associations with breast cancer risk BRCA1, BRCA2, PALB2, ARD1, RAD51C, RAD51D, ATM, and CHEK2. Both studies were published in the New England Journal of Medicine. The first, by Fergus J. Couch, PhD, of the Mayo Clinic in Rochester, Minnesota, and colleagues, looked at a panel of 28 cancer-predisposition genes in approximately 64,000 women from the United States (32,247 with breast cancer). The team analyzed germline pathogenic variants using data from women in the Cancer Risk Estimates Related to Susceptibility (CARRIERS) consortium and found pathogenic variants in 12 established breast cancer predisposition genes in 5.03% of women with breast cancer compared with 1.63% of controls.

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