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Jacobio Announces FDA Approves IND Application to Develop KRAS G12C Inhibitor
The clinical trials of KRAS G12C inhibitors are expected to enroll patients in the second half of 2021. Jacobio is aiming for the in-house combination therapy of KRAS G12C and SHP2 inhibitors. Inhibitors targeting KRAS G12D and KRAS G12V mutations have lead compounds.
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BEIJING and SHANGHAI and BOSTON, May 2, 2021 /PRNewswire/ Jacobio Pharmaceuticals (1167.HK) has announced the U.S. Food and Drug Administration (FDA) has approved company s Investigational New Drug (IND) application to develop a KRAS G12C inhibitor. IND application to the National Medical Products Administration (NMPA) in China was accepted on March 17. It will be used to treat advanced solid tumors with the KRAS G12C mutation, including but not limited to non-small cell lung cancer (NSCLC), colorectal cancer (CRC) and other advanced solid tumors. Patient enrollment for clinic
Inside a high-security lab that is testing products against COVID-19
In a nondescript building in Virginia, a lab is on the front lines against COVID-19.
and last updated 2021-02-10 12:13:22-05
STERLING, Va. â Behind high-security, pressurized doors is one of the labs on the front lines of the coronavirus pandemic.
âOur work is recognized by the whole industry,â said Dr. Steve Zhou, director of virology and microbiology for Microbac.
The Microbac lab one of only a handful in the world approved by the CDC to cultivate and test the live SARS-CoV-2 virus, commonly known as COVID-19.
âOften, they go to a third-party lab for expertise and for directly regulatory knowledge and also for speed, because weâre specialized in this,â Dr. Zhou said.