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Nonstatin Lipid-Lowering Agents

Dr Michos discusses safety and efficacy of available nonstatin therapies and emerging agents for treating hyperlipidemia.

Keithc ferdinandErind michosLipid loweringLdl cBempedoic acidStatin intolerant patientsLipoportein aIsacopent ethylCombination therapyCardiovascular disease

Study Suggests Bempedoic Acid Could Find Role in Primary Prevention

An analysis of a primary prevention subgroup within the CLEAR Outcomes trial presented at ADA 2023 suggests use of bempedoic acid was associated with a 30% relative risk reduction for MACE among this patient population.

United statesCampbellp bempedoicStevene nissenDhruv kaziScientific sessions of the american diabetes associationBeth israel deaconess medical centerAmerican college of cardiologyOutcomes researchThoracic institute at cleveland clinicSmith centerScientific sessionsAmerican diabetes associationAmerican collegeThoracic instituteNew england journalCardiac critical care unit

Esperion Presents Results from CLEAR Outcomes Primary Prevention Analysis at 83rd American Diabetes Association Scientific Sessions

Esperion Presents Results from CLEAR Outcomes Primary Prevention Analysis at 83rd American Diabetes Association Scientific Sessions
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United statesSouth australiaTiffany aldrichJoanne foodyAlexis callahanStephen nichollsSheldon koenigMonash universityJournal of the american medical associationExchange commissionAmerican diabetes associationAmerican medical associationPrimary preventionCardiovascular eventsStatin intolerant patientsVictorian heart hospital

Esperion Presents Results from CLEAR Outcomes Primary Prevention Analysis at 83rd American Diabetes Association Scientific Sessions

Esperion Presents Results from CLEAR Outcomes Primary Prevention Analysis at 83rd American Diabetes Association Scientific Sessions
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United statesSheldon koenigJournal of the american medical associationAmerican diabetes associationAmerican medical associationPrimary preventionCardiovascular eventsStatin intolerant patients

Esperion Presents Results from CLEAR Outcomes Primary

– 30% risk reduction of MACE-4 composite of death from cardiovascular causes, and >25% risk reduction across four key secondary endpoints in primary.

South australiaUnited statesStephen nichollsTiffany aldrichJoanne foodyAlexis callahanSheldon koenigExchange commissionMonash universityJournal of the american medical associationAmerican diabetes associationAmerican medical associationPrimary preventionCardiovascular eventsStatin intolerant patientsVictorian heart hospital

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