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LSU Health New Orleans describes a causal mechanism of link between cancer and obesity

E-Mail New Orleans, LA - A review study led by Maria D. Sanchez-Pino, PhD, an assistant research professor in the departments of Interdisciplinary Oncology and Genetics at LSU Health New Orleans School of Medicine and Stanley S. Scott Cancer Center, advances knowledge about the connection between obesity-associated inflammation and cancer. The researchers suggest that inflammatory cells with immunosuppressive properties may act as a critical biological link between obesity and cancer risk, progression, and metastasis. The paper is published in the June 2021 issue of Obesity, available here. Despite evidence showing that obesity increases the risk of cancer progression, efforts are needed to identify the causal relationship between immunosuppressive cells and the response of immunotherapy in patients with obesity.

United statesNew orleansUniversity of texas southwestern medical centerBaton rougeLinda anne gilmoreAugusto ochoaMariad sanchez pinoJustin brownNational institute of diabetesSchool of medicineNational institutes of health centerTranslational sciencesHealth new orleansHealth new orlean school of medicineNational instituteSchool of public health

Obesity and cancer: Studies highlight different aspects of the connection

Obesity and cancer: Studies highlight different aspects of the connection
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United statesNew orleansUniversity of texas southwestern medical centerBaton rougeAugusto ochoaLinda anne gilmoreXiacheng wuHenry thompsonJovanny zabaletaLas vegasTanya agurs collinsMariad sanchez pinoJustin brownTiffany carsonLucio mieleShengping yang

Study finds mechanism leading to herceptin resistance and Rx approach to reverse it

E-Mail New Orleans, LA - Research conducted by an international team of scientists discovered a mechanism that leads to Herceptin resistance, representing a significant clinical obstacle to successfully treating HER2-positive breast cancer. They also identified a new approach to potentially overcome it. The work is published online in Nature Communications, available here. This work attempts to understand why some HER2-positive breast cancer patients do not benefit from treatment with Herceptin, which is a generally effective HER2-targeted therapy, explains Bolin Liu, MD, Professor of Genetics at LSU Health New Orleans School of Medicine and Stanley S. Scott Cancer Center.

United statesNew orleansBaton rougeHongsheng liDying songXiaoting jiaZhijie zhangZhao liuHui lyuLiyun luoJiansheng liBolin liuGuopei zhengSchool of medicineNature communicationsGuangdong special support program

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM
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New orleansUnited statesBaton rougeNew orleansJoel bainesMichaela stubblefieldKonstantin gus kousoulasSamithamby jeyaseelanAugusto ochoRhonda cardinEmily hendersonSouthern universityBiomedical research excellenceNational cancer instituteNational institutes of healthCancer center

$1m grant funds research on potential new RX for prostate cancer

$1m grant funds research on potential new RX for prostate cancer
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New orleansUnited statesBaton rougeSteve nelsonHari koulDevelopment branch of the veterans administrationSchool of medicineNational cancer instituteSchool of public healthSchool of dentistryHealth new orleansSchools of allied health professionsBiomedical laboratory researchStanleys scott cancer centerHealth new orleans school of medicineOrleans va medical center