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Opportunities to improve future HIV vaccine candidates

Opportunities to improve future HIV vaccine candidates
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Laboratory of immunoregulationSpecific immunity section

NIAID study identifies critical t-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

Laboratory of immunoregulationNih national institute of allergyNational institute of allergyNational institutes of healthNational instituteInfectious diseasesNational institutesSpecific immunity sectionImmune responseImmune systemInfectious diseasesMedical researchT cell

NIH research identifies opportunities to impr

<p>An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues. The study findings, appearing in Science, draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called “long-term non-progressors” or “elite controllers” (LTNPs/ECs).</p>

United statesMark connorsHuman servicesLaboratory of immunoregulationUs department of healthNational institutes of healthNational institute of allergyNews science writing branchNational instituteInfectious diseasesNational institutesSpecific immunity sectionLow antigen receptorScience writing branch

NIH Study Finds Ways to Enhance Future HIV Vaccines

NIH Study Finds Ways to Enhance Future HIV Vaccines
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Mark connorsNational institutes of healthLaboratory of immunoregulationNational institute of allergyNational instituteInfectious diseasesNational institutesSpecific immunity sectionLow antigen receptor

NIH research identifies opportunities to impr

<p>An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues. The study findings, appearing in Science, draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called “long-term non-progressors” or “elite controllers” (LTNPs/ECs).</p>

United statesMark connorsHuman servicesLaboratory of immunoregulationNews science writing branchNational institute of allergyNational institutes of healthUs department of healthNational instituteInfectious diseasesNational institutesSpecific immunity sectionLow antigen receptorScience writing branch