Microglial activation is critical for modulating the neuroinflammatory process and the pathological progression of neurodegenerative diseases, such as Alzheimer's disease (AD). Microglia are involved in forming barriers around extracellular neuritic plaques and the phagocytosis of β-amyloid peptide (Aβ). In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells. Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Maxillary bone loss and local periodontal tissue inflammation associated with the development of PD were confirmed by morphometric bone analysis and cytokine expression, respectively. The frequency and the total number of activated microglia (CD45+ CD11b+ MHCII+) in the brain were analyzed by flow cytometry. Mouse m
– Comprehensive evaluation of all opportunities and risks in the market.
– Tryptic Soy Agar (TSA) market ongoing developments and significant occasions.
– Detailed study of business techniques for development of the market-driving players.
– Conclusive study about the improvement plot of market for approaching years.
– Top to bottom appreciation of market-express drivers, targets and major littler scale markets.
– Favorable impression inside imperative mechanical and publicize latest examples striking the market.
Table of Contents:
Chapter Two: Manufacturing Technology of Product
Chapter Three: Analysis of Global Key Manufacturers
Chapter Four: 2015-2020 Global Market of Tryptic Soy Agar (TSA)
Chapter Five: Market Status of Industry
Chapter Six: 2020-2025 Market Forecast of Global Tryptic Soy Agar (TSA) Industry